| Unlockable: | How to Unlock: |
| Ammand The Corsair | Complete the Pirate Poker sub-mission on the Shipwreck City level. |
| Black Bart | Complete the Combat Challenge on the Maelstrom level. |
| Bootstrap Bill Turner | Complete the Defeat Enemies sub-mission on the Prison Fortress level. |
| Cannon Arm | Complete the Combat Challenge on the Pearl vs. Kraken level. |
| Capitain Chevalle | Complete the Port Royal level. |
| Captain Barbossa | Complete the Shipwreck City level. |
| Captain Elizabeth Swann | Complete the Combo Challenge on the Davy Jones Locker level. |
| Captain Jack Sparrow | Complete the Prison Fortress level. |
| Captain Sao Feng | Complete the Singapore level. |
| Captain Teauge | Complete the Combat Challenge on the Prison Fortress level. |
| Cotton | Complete the Rescue sub-mission on the Isla de Pelegostos level. |
| Davy Jones | Complete Pearl vs. Dutchman level. |
| Elizabeth Swann | Complete the Tortuga level. |
| Gentlemen Jocard | Complete the Davy Jones Locker level. |
| Gibbs | Complete the Combat Challenge on the Port Royal level. |
| Governor Swann | Complete the Combat Challenge on the Pearl vs. Dutchman level. |
| James Norrington | Complete the Combat Challenge on the Tortuga level. |
| Lian | Complete the Combat Challenge on the Singapore level. |
| Lord Cuttler Beckett | Complete the Maelstrom level. |
| Mercer | Complete the Hit-Combo sub-mission on the Singapore level. |
| Mistress Ching | Complete the Jackanism on the Tortuga level. |
| Mordillah | Complete the Combo Challenge on the Prison Fortress level. |
| Pintel | Complete the Isla Cruces level. |
| Ragetti | Complete the Combat Challenge on the Isla Cruces level. |
| Sri Sumba Jee | Complete the Combat Challenge on the Shipwreck City level. |
| Tai Huang | Complete the Sea Battle level. |
| Tia Dalma | Complete the Missing Person sub-mission on the Port Royal level. |
| Villanueva | Complete the Combo Challenge on the Tortuga level. |
| Will Turner | Complete the Isla de Pelegostos level. |
| Unlockable: | How to Unlock: |
| Collect 100 Souls (150 points) | Collect one hundred souls from your enemies using the power of the Jackanism sword. |
| Davy Jones' Locker Treasure (25 points) | Open the Jackanism chest of Davy Jones' Locker, and unlock bonus material in the Treasure Trove. |
| Eleven Calypso Pieces (150 points) | Find the hidden Calypso piece on each level to unlock the story of Davy Jones and Calypso. |
| Elizabeth's fourth finish move (25 points) | Unlock Elizabeth's fourth finish move by exploring and escaping from Singapore. |
| Elizabeth's second finish move (25 points) | Unlock Elizabeth's second finish move by locating Mistress Ching and Villanueva in Tortuga. |
| Elizabeth's third finish move (25 points) | Unlock Elizabeth's third finish move by surviving Isla Cruces. |
| Isla Cruces Treasure (25 points) | Open the Jackanism chest in Isla Cruces, and unlock bonus material in the Treasure Trove. |
| Jack's fourth finish move (25 points) | Unlock Jack's fourth finish move by escaping from Davy Jones' Locker. |
| Jack's second finish move (25 points) | Unlock Jack's second finish move by escaping from the Prison Fortress. |
| Jack's third finish move (25 points) | Unlock Jack's third finish move by surviving the Kraken's attack. |
| Port Royal Treasure (25 points) | Open the Jackanism chest in Port Royal, and unlock bonus material in the Treasure Trove. |
| Prison Fortress Treasure (25 points) | Open the Jackanism chest in the Prison Fortress, and unlock bonus material in the Treasure Trove. |
| Seven Bottles of Rum (25 points) | Collect the seven bottles of Rum (hidden in the Black Pearl) during the Kraken's attack. |
| Seven Gold Bars (25 points) | Gold - every pirate's dream! Collect the seven gold bars of Shipwreck City. |
| Seven Letters (25 points) | Collect all seven Letters, lost throughout the Prison Fortress. |
| Seven Nautilus Shells (25 points) | Collect the seven Nautilus shells, scattered throughout the Flying Dutchman. |
| Seven Paprika Tins (25 points) | Collect the seven Paprika tins of Isla Cruces. |
| Seven Periwigs (25 points) | Collect the seven Periwigs hidden around Port Royal. |
| Seven Pirate Flags (25 points) | Collect the seven Pirate Flags of Tortuga, hidden in chests and secret areas. |
| Seven Pirate's Dice (25 points) | Collect the seven Pirate's dice, lost around the Flying Dutchman and the Black Pearl. |
| Seven Sea Charts (25 points) | Collect the seven Sea Charts from the streets of Singapore. |
| Seven Skulls (25 points) | Collect the seven Skulls hidden throughout Davy Jones' Locker. |
| Seven Tarot Cards (25 points) | Collect the seven Tarot cards lost around the Flying Dutchman. |
| Shipwreck City Treasure (25 points) | Open the Jackanism chest in Shipwreck City, and unlock bonus material in the Treasure Trove. |
| The Kraken Treasure (25 points) | Open the Jackanism chest in the Black Pearl, and unlock bonus material in the Treasure Trove. |
| The Maelstrom Treasure (25 points) | Open the Jackanism chest of the Maelstrom, and unlock bonus material in the Treasure Trove. |
| Tortuga Treasure (25 points) | Open the Jackanism chest of Tortuga, and unlock bonus material in the Treasure Trove. |
| Will's fourth finish move (25 points) | Unlock Will's fourth finish move by surviving Isla Cruces. |
| Will's second finish move (25 points) | Unlock Will's second finish move by saving Chevalle and leaving Port Royal. |
| Will's third finish move (25 points) | Unlock Will's third finish move by stealing the key from the Flying Dutchman. |