| Unlockable: | How to Unlock: |
| 100K Club - 10 points | Get 100,000 points in a song. |
| 200K Club - 10 points | Get 200,000 points in a song. |
| 200K Pair - 30 points | Get 200,000 points on a song in Cooperative. |
| 300K Club - 30 points | Get 300,000 points in a song. |
| 400K Club - 30 points | Get 400,000 points in a song. |
| 400K Pair - 30 points | Get 400,000 points on a song in Cooperative. |
| 600K Pair - 30 points | Get 600,000 points on a song in Cooperative. |
| 800K Pair - 30 points | Get 800,000 points on a song in Cooperative. |
| Axe Grinder - 10 points | Unlock Rock City Theater. |
| Big Spender Award - 10 points | Spend $10,000 at the store. |
| Champagne Room V.I.P. - 30 points | Get 500,000 points in a song. |
| Dimebag Darrell Award - 10 points | Get a 100 note streak. |
| Easy Tour Champ - 10 points | Beat the Easy tour. |
| Eddie Van Halen Award - 30 points | Get a 500 note streak. |
| Expert Tour Champ - 30 points | Beat the Expert tour. |
| Extra Credit Award - 10 points | View the credits. |
| Fanatical Completionist Award - 30 points | Buy all guitar finishes. |
| Fashion Plate Award - 10 points | Buy all outfits. |
| Gear Head Award - 30 points | Buy all guitars. |
| Guitar Hero - 10 points | Unlock Stonehenge. |
| Guitarmaggedon Award - 30 points | Earn five stars on all songs in the Hard tour. |
| Hard Tour Champ - 30 points | Beat the Hard tour. |
| Hendrix Award - 10 points | Beat a song with lefty flip on. |
| Joan & Lita Award - 30 points | Get a 100 note streak in Cooperative. |
| Joe & Steven Award - 30 points | Get a 500 note streak in Cooperative. |
| Keef & Mick Award - 30 points | Get a 1000 note streak in Cooperative. |
| Kick the Bucket Award - 30 points | Beat Jordan on Expert. |
| Lennon & McCartney Award - 10 points | Get an 8x streak in Cooperative. |
| Life of the Party Award - 10 points | Buy all characters. |
| Long Road Ahead Award - 10 points | Fail a song on Easy. |
| Medium Tour Champ - 30 points | Beat the Medium tour. |
| Millionaire Pair - 30 points | Get 1,000,000 points on a song in Cooperative. |
| Most Likely to Succeed Award - 30 points | Earn five stars on all songs in the Medium tour. |
| New Kid - 10 points | Unlock Blackout Bar. |
| Page & Plant Award - 30 points | Get 100% notes hit on a song in Cooperative. |
| Perfectionist Award - 30 points | Get 100% notes hit on a song. |
| Record Collector Award - 10 points | Buy all songs |
| Roadie - 10 points | Unlock Rat Cellar. |
| Rock School Grad - 10 points | Complete all tutorials. |
| Rock Snob Award - 10 points | Refuse to play an encore. |
| Rock Star - 10 points | Unlock Harmonix Arena. |
| Sandbox Hero Award - 30 points | Earn five stars on all songs in the Easy tour. |
| Saturday Morning Award - 10 points | Beat Trogdor and Thunder Horse. |
| Scenester Award - 10 points | Beat all the unlock songs. |
| Scoremonger Award - 10 points | Get an 8x multiplier. |
| Shredder - 10 points | Unlock Vans Warped Tour. |
| Start a Real Band Already Award - 30 points | Earn five stars on all songs in the Expert tour. |
| Teacher's Pet Award - 10 points | Practice three different songs. |
| Yngwie Malmsteen Award - 30 points | Get a 1000 note streak. |
| Young Gun - 10 points | Unlock RedOctane Club. |